معرفی
D. (Dick) Hoekstra is a Professor at the Faculty of Medical Sciences of the University of Groningen (UMCG). His research focuses on cell biology, neuroscience, and biophysics, particularly the molecular mechanisms underlying myelin biogenesis and oligodendrocyte function. He investigates how lipids, protein dynamics, and extracellular matrix interactions influence neurological disorders like multiple sclerosis. His work also explores nanotechnology applications for drug delivery across the blood-brain barrier.
- Professor, Faculty of Medical Sciences, University of Groningen (UMCG)
- Deputy Chairman, Biochemical Journal
Research Interests:
- Myelin biology and oligodendrocyte membrane dynamics
- Lipid-protein interactions in neurodegenerative diseases
- Transcytosis-mediated drug delivery systems
- Extracellular matrix regulation of remyelination
- Molecular mechanisms of demyelination
- Nanocarrier design for CNS therapeutics
Key Publications (recent trends):
- 2018: MMP7 and fibronectin in chronic MS lesions
- 2017: GD1a's role in myelination via PKA activation
- 2016: MAL protein in myelin protein trafficking
- 2016: Oligodendroglial membrane dynamics review
- 2015: Blood-brain barrier transcytosis review
Contact: d.hoekstra@umcg.nl
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