Crystal M. Weyman

Dr. Crystal M. Weyman is a Professor and Chair of the Biological, Geological and Environmental Sciences Department at Cleveland State University's College of Arts and Sciences. She serves on the Planning Committee for the Center for Gene Regulation in Health and Disease (GRHD) and is listed as Regular and Research Faculty for GRHD. Her office is located in Science and Research Building, Room 266.

Dr. Weyman's research focuses on understanding the signaling pathways that coordinately regulate the mutually exclusive biological endpoints of differentiation and apoptosis (programmed cell death) in skeletal myoblasts. Her laboratory also investigates signaling by oncogenic Ras. Dissecting this coordinate regulation could enable selective manipulation relevant to the amelioration of disease states associated with muscle degeneration and to the effectiveness of any treatment utilizing skeletal myoblast transfer.

Analysis of Dr. Weyman's publications reveals a consistent research trajectory spanning over three decades, with a primary focus on skeletal myoblast differentiation, apoptosis regulation, and oncogenic Ras signaling. Her work demonstrates increasing sophistication in molecular techniques, with recent publications focusing on microRNA regulation, transcriptional control mechanisms involving MyoD and p53, and the role of specific proteins like PUMA in apoptosis pathways. Her research has broad implications for understanding muscle degeneration diseases and cancer biology.

Dr. Weyman leads an active research laboratory with several PhD students and post-doctoral fellows. She has secured research funding that supports her laboratory's work, though specific grant details are not provided in the available information. Her collaborative approach is evident through her numerous co-authored publications with researchers across multiple institutions.

Her laboratory team includes Dr. Jane Yoder Hill (Post-doctoral fellow), Fatima Said (PhD Student), Bryce Waldal (PhD Student), and Ara Mendez (PhD Student), who work together on projects related to skeletal myoblast differentiation and apoptosis pathways.