Claudia Waskow

Claudia Waskow is a Group Leader at the Leibniz Institute on Aging (FLI) in Jena, Germany, with additional affiliation at the Institute for Immunology at the Medical Faculty Carl Gustav Carus, Technical University Dresden. Her research focuses on the Immunology of Aging, particularly the regulation of hematopoietic stem cells (HSCs) in steady-state and inflammatory conditions, spanning embryonic development to aged organisms.

• University: Leibniz Institute on Aging (FLI)
• School: Faculty of Biological Sciences
• Department: Research Group Waskow
• Academic Rank: Researcher

Her team investigates cell-intrinsic and niche-mediated signals controlling HSC fate decisions, with applications in blood disorders, regenerative medicine, and immunosenescence. Key projects include XpandHSC (Leibniz SAW program) and collaborations within the German Stem Cell Network (GSCN) and DFG Excellence Cluster Balance of the Microverse.

Recent publications highlight her work on macrophage-stem cell interactions, signaling pathways (e.g., PGE2/cAMP, WNT5A), and humanized mouse models for studying HSC function. The group also explores mesenchymal stromal cell regulation of HSC survival and RelB-dependent immune tolerance mechanisms.

The Waskow group collaborates with institutes like the German Stem Cell Network, DFG CRC1278 Polytarget, and IMPULS Center for Age Research, supported by grants from the Leibniz Association and DFG.