Claire Brown

Claire Brown is a Professor in the Department of Physiology at McGill University's Faculty of Medicine, serving as Director of the Advanced BioImaging Facility (ABIF). She additionally manages the Cell Imaging and Analysis Network (CIAN) and Cystic Fibrosis Translation Research Centre (CFTRc) light microscopes. With over 25 years of expertise in quantitative bioimaging, she oversees 18 research microscopes and a support team serving approximately 200 users from 80 laboratories across Montreal and Canada.

Education:

• B.Sc. from Saint Mary's University
• Ph.D. from the University of Western Ontario

Research Interests: Dr. Brown's work centers on quantitative bioimaging, applying biophysical techniques to fluorescence microscopy to quantify protein dynamics and interactions. Her research elucidates molecular mechanisms of cell adhesion and migration, with implications for breast cancer metastasis. She pioneers methods to minimize phototoxicity in live-cell imaging and develops rigorous quality control standards for microscopy to enhance data reproducibility.

Publication Trends: Recent publications (2023-2025) highlight her leadership in global initiatives for FAIR (Findable, Accessible, Interoperable, Reusable) data management, antibody validation frameworks, and microscopy quality standards. She co-develops software tools (e.g., Micro-Meta App) for metadata collection and promotes community-driven protocols to address reproducibility challenges. Her work increasingly focuses on equitable access to imaging technologies in resource-limited settings.

Facilities and Training: Under her direction, ABIF, CIAN, and CFTRc offer expertise in advanced techniques including TIRF, FLIM, and multi-photon microscopy. She has established over 80 workshops, notably the Montreal Light Microscopy Course, fostering skills development for researchers worldwide.