معرفی
Ciprian P. Gheorghe, MD, PhD, serves as Assistant Professor in both the Department of Gynecology and Obstetrics and the Physiology Division of Basic Sciences at Loma Linda University School of Medicine, where he conducts interdisciplinary research bridging obstetrics, physiology, and molecular medicine.
His academic credentials include:
- Doctor of Medicine (MD) from Loma Linda University (2008)
- Doctor of Philosophy (PhD) from Loma Linda University (2006)
Dr. Gheorghe's research centers on maternal-fetal medicine with emphasis on environmental impacts on fetal development, placental molecular pathways, and innovative interventions. Key areas include wildfire exposure effects on congenital heart defects, gestational hypoxia-induced pulmonary remodeling, nitric oxide signaling in placental iron metabolism, and molecular mechanisms of glucocorticoid response in preterm newborns. His work integrates multi-omics approaches and translational models to address critical perinatal complications.
Analysis of his 2021-2025 publications reveals consistent themes in perinatal pathophysiology, with growing focus on environmental stressors (wildfires, hypoxia) and molecular mechanisms (exosomal miRNAs, epitranscriptomics). His recent work demonstrates increasing collaboration with virology and genomics teams, particularly regarding SARS-CoV-2 pathogenesis and therapeutic development.
Dr. Gheorghe actively mentors graduate students through his extensive grant portfolio, which includes NIH-funded projects on umbilical cord milking (NICHD 2024-2025), gastroschisis outcomes (MCW 2020-2023), and vertical SARS-CoV-2 transmission. His $1.2M+ in active funding spans federal, industry (Karl Storz, Alydia Health), and institutional sources, supporting both clinical trials and basic science investigations into fetal programming and placental dysfunction.
His research operates within Loma Linda University's Center for Perinatal Biology and the Charles and Nancy Sims Institute for Genetics & Translational Genomics Research, where he directs the BioBank and Database project. These resources enable longitudinal studies of gastroschisis, TTTS, and placental biomarkers through integrated clinical and molecular analytics.
