Christophe Lenglet

Christophe Lenglet is an Associate Professor at the University of Minnesota, affiliated with the Department of Biomedical Engineering and the Department of Electrical and Computer Engineering. He is part of the PhD Program in Medical Physics and the Center for Magnetic Resonance Research. His work focuses on advanced neuroimaging techniques, particularly MRI methodologies for studying neurological disorders such as Friedreich ataxia, spinocerebellar ataxias, and spinal cord degeneration.

Research interests include biophysical modeling of brain microstructure, development of quantitative MRI protocols (e.g., HARDI-ZOOMit), and applications in neurodegenerative diseases. Key projects involve the TRACK-FA study for Friedreich ataxia natural history tracking and ENIGMA-Ataxia consortium collaborations to standardize MRI biomarkers.

Publications emphasize spinal cord and brain imaging in ataxias, diffusion MRI techniques, and clinical trial support for therapies like leriglitazone. His work bridges biomedical engineering, radiology, and neurology to advance diagnostic and monitoring tools for neurodegenerative diseases.