معرفی
Dr. Christine Basmadjian is a researcher affiliated with Newcastle University, focusing on interdisciplinary studies at the intersection of biochemistry, pharmacology, and cancer biology. Her work spans drug discovery, molecular signaling, and therapeutic interventions targeting diseases like cancer, inflammatory disorders, and infectious diseases. She has collaborated on projects involving flavaglines, kinase inhibitors, and mitochondrial protectants.
Her research interests include:
- Design and evaluation of covalent inhibitors for kinases like NIK
- Pharmacological profiling of flavaglines for anti-inflammatory and anticancer activity
- Mechanistic studies of TRPM6 channels and STAT3 signaling in drug interactions
- Investigating resistance mechanisms in anti-BRAF/MEK therapies via eIF4F regulation
Publications from 2014–2021 reveal a focus on translating chemical biology into therapeutic strategies, with a particular emphasis on flavagline derivatives and kinase inhibition. While no specific awards or students are documented in this dataset, her contributions to drug development and molecular pharmacology underscore her role in advancing targeted therapies.
