معرفی
Christina Farr, PhD, is an Assistant Professor in the Department of Pathology at Case Western Reserve University School of Medicine. She holds affiliations with the Center for Global Health and Diseases and the Population and Cancer Prevention Program at the Case Comprehensive Cancer Center. Her research focuses on host-microbe interactions in reproductive health, employing systems immunology approaches combining clinical, model system, and bioinformatics tools. Key areas of interest include mucosal immunology of the female genital tract, sexually transmitted infections, preterm birth mechanisms, and microbiome dynamics.
Dr. Farr earned her PhD in Microbiology and Immunology from the University of British Columbia. Her work integrates immunological assays, flow cytometry, and advanced sequencing techniques to study vaginal microbiome composition and its impact on HIV susceptibility and contraceptive effects. She collaborates widely, contributing to studies like the THRIVE observational study examining bacterial vaginosis and the neovaginal microbiome in transgender individuals.
Her recent research highlights the role of vaginal microbiome shifts in HIV acquisition risk, the effects of hormonal contraceptives on mucosal immunity, and the development of novel microbicides. Key publications address dapivirine vaginal ring impacts, depot medroxyprogesterone acetate effects, and neutrophil-driven inflammation in dysbiotic microbiomes.
Dr. Farr's grants and funding support investigations into microbiome-proteome interactions, HPV prevalence in transfeminine individuals, and the vaginal-vulvar microbiome in lichen sclerosus. Her lab works at the intersection of immunology, microbiology, and global health to advance reproductive tract disease prevention strategies.
