معرفی
Christian Schwerk is a Professor at the Mannheim Medical Faculty of Heidelberg University, specializing in the functional mechanisms of blood-brain barriers and their role in innate immunity. His research focuses on how endothelial and epithelial cells regulate immune and cancer cell transmigration during health and disease.
- Current affiliation: Heidelberg University (Mannheim Medical Faculty)
- Research areas: Blood-brain barrier biology, host-pathogen interactions, neuroinflammation, immune cell trafficking
His work employs in vitro models to study pathogenic conditions, particularly examining gene expression regulation, cytokine production, and signal transduction pathways in barrier cells. Recent publications highlight his investigations into tumor cell invasion, meningococcal infections, and immune cell transmigration across the blood-cerebrospinal fluid barrier.
Studies include molecular mechanisms of bacterial interactions with barrier cells and the role of IκBζ in pro-inflammatory responses. His research contributes to understanding CNS protection strategies against pathogens and metastatic cells.
