معرفی
Dr. Chris MacDonald is a Senior Lecturer in Biomedical Sciences at the Department of Biology, University of York. His research focuses on understanding mechanisms of cell surface protein trafficking using yeast as a model organism. Key areas include endosomal recycling, nutrient stress responses, and the role of lipid and signaling pathways in regulating membrane dynamics.
His work combines genetic screens, live-cell imaging, and biochemical approaches to uncover conserved machinery involved in protein trafficking. Notable contributions include discoveries about glucose starvation effects on endosomal recycling and the role of COG complexes in defense mechanisms. He has collaborated on projects funded by BBSRC, including the PALM/STORM/SIM Super Resolution Microscopy initiative.
MacDonald’s research also explores eisosome compartments and molecular crowding in yeast, with implications for understanding cellular responses to environmental stress. He advises outreach programs like 'Beyond bread: How Baker’s yeast can be used to understand cell biology' and has contributed to datasets on protein aggregation markers.
