Chris Link

Chris Link serves as an Associate Professor in the Department of Integrative Physiology at the University of Colorado Boulder, with dual affiliation at the Institute for Behavioral Genetics. His laboratory operates at the intersection of molecular genetics and neurodegenerative disease research.

Dr. Link's research program focuses on molecular mechanisms underlying age-associated neurodegenerative disorders, particularly through C. elegans modeling systems. His work examines protein aggregation phenomena in Alzheimer's disease and related conditions, investigating how beta-amyloid peptides function as modular aggregation domains and how engineered proteins can model neurodegenerative processes. The laboratory employs transgenic worm models to dissect fundamental cellular and molecular pathways involved in neurodegeneration.

Analysis of Dr. Link's publication record reveals consistent focus on protein aggregation mechanisms in neurodegenerative processes, with particular emphasis on Alzheimer's disease modeling through C. elegans systems. His work bridges molecular biology, protein engineering, and neurogenetics to understand fundamental disease mechanisms.

Dr. Link maintains an active research laboratory focused on neurodegenerative disease mechanisms, operating the Neurodegenerative Disease Laboratory at the University of Colorado. His team employs C. elegans as a primary model system for investigating protein aggregation and cellular toxicity pathways relevant to human neurological disorders.