Chris Hartley

Chris Hartley, M.D. is a Physician Scientist at Mayo Clinic's Department of Laboratory Medicine and Pathology, specializing in gastrointestinal and liver pathology, cytopathology, and pancreatobiliary cytology. He completed his MD at Wake Forest University School of Medicine (2012) and fellowships at Washington University School of Medicine (2018) and University of Wisconsin Hospital (2017).

• 2018 Fellow - Liver and Gastrointestinal Pathology
• 2017 Fellow - Cytopathology
• 2016 Resident - Anatomic & Clinical Pathology

Hartley's research integrates artificial intelligence with cytopathology and histopathology, focusing on improving diagnostic accuracy for pancreatic ductal adenocarcinoma, colonic graft-versus-host disease, and hepatocellular carcinoma. His work explores AI-driven tools for bile duct brushing evaluation and spatially resolved iron quantification in liver samples.

Recent publications highlight his leadership in digital pathology and AI applications across gastrointestinal, hepatic, and pulmonary diseases. Key trends include:

• AI for histologic differentiation in cancers
• Cytomorphologic studies of rare neoplasms
• Molecular marker analysis in transplant-related pathologies

Scientific recognitions include:

• 2019 'Good Catch' Patient Safety Award
• 2017 Young Investigator Award - Cancer Cytopathology
• 2015 USCAP Abstract Award Runner-up

As a member of the Rodger C. Haggitt Gastrointestinal Pathology Society and American Society for Clinical Pathology, Hartley contributes to precision medicine initiatives and multidisciplinary cancer care teams.