معرفی
Dr. Chien-wen Kuo is a Research Fellow in the Cardiovascular & Metabolic Health department at the University of Glasgow. His work focuses on protein palmitoylation, post-translational modifications, and their implications in cardiovascular physiology and pathology.
Research Interests: Dr. Kuo investigates the molecular mechanisms of protein palmitoylation, particularly its role in regulating ion channels (e.g., Ca(v)1.2, TrpM7), calcium signaling, and protein interactions in cardiac myocytes. His research bridges biochemical enzymology and therapeutic applications for cardiovascular diseases.
Publication Trends: His recent work (2021–2025) emphasizes protein engineering (e.g., nanobody-thioesterase chimeras), enzymatic regulation of palmitoylation, and the impact of cysteine modifications on cellular physiology. Collaborations span structural biology and metabolic health disciplines.
Collaborations: Dr. Kuo collaborates with researchers like Fiona Ashford, Emma Dunning, Elaine Brown, and William Fuller on projects related to caveolin-3 interactions and cardiac pathologies.
