معرفی
Cheryl Ingram-Smith is an Associate Professor and Graduate Program Director in the Department of Genetics and Biochemistry at Clemson University's College of Science. Her research focuses on the pathogenic mechanisms of Entamoeba histolytica, a leading cause of amoebic dysentery. She holds a BS in Biology from MIT (1986) and a PhD in Molecular Biology from the University of Pennsylvania (1993).
Dr. Ingram-Smith leads a lab studying how this parasite adapts to intestinal environments, particularly glycogen metabolism and encystation processes. Her lab employs axenic culture systems to investigate encystation regulation and enzyme functions like acetate kinase activity. Current research emphasizes metabolic pathways enabling parasite survival and pathogenesis.
Teaching responsibilities include Molecular Biochemistry (BCHM 3010) and Independent Research (BCHM/GEN 4910). She has advised over 10 graduate students and regularly mentors undergraduates. Her work is supported through collaborative efforts with the Eukaryotic Pathogens Innovation Center (EPIC).
Publications span enzyme characterization (acetate kinase, acetyl-CoA synthetase) and structural biology, with over 35 peer-reviewed articles. Ongoing projects explore novel metabolic pathways in protozoan and fungal pathogens, with implications for drug development targeting energy production mechanisms.
