Charlie Wang

Charlie Wang, MD, PhD is an Assistant Professor in the Department of Radiology at the University of California, San Francisco (UCSF) School of Medicine, where he conducts cutting-edge research in advanced magnetic resonance imaging techniques.

His primary research interests include:

• Magnetic Resonance Fingerprinting (MRF)
• Hyperpolarized MRI for metabolic imaging
• Phosphorus-31 spectroscopic imaging
• Quantitative MRI methods development
• Applications in neuroscience, oncology, and cardiology

Dr. Wang's research focuses on developing novel imaging techniques to measure metabolic processes and tissue properties non-invasively. His recent work has advanced hyperpolarized [13C,15N2]urea MRI for human brain perfusion studies and improved kinetic rate estimation with hyperpolarized [1-13C]pyruvate MRI. His publications demonstrate significant contributions to quantitative imaging biomarkers, metabolic imaging, and the translation of advanced techniques from preclinical to clinical applications.

His work spans several key technical areas:

• Development of MRF techniques with quadratic RF phase for simultaneous measurement of multiple tissue parameters
• Creation of phosphorus-31 spectroscopic methods for creatine kinase activity quantification
• Improvement of motion artifact suppression in preclinical imaging
• Development of high-resolution dynamic imaging techniques for brain studies

Dr. Wang maintains productive collaborations with researchers at UCSF, particularly with experts in hyperpolarized MRI including Peder Larson and Daniel Vigneron. His work bridges engineering, physics, and clinical applications to advance diagnostic capabilities in medicine.