Charles V. Rice

Charles V. Rice is an Associate Professor in the Department of Chemistry and Biochemistry at The University of Oklahoma. His research focuses on developing novel therapies against antibiotic-resistant bacteria, particularly targeting biofilms, inflammatory responses, and antimicrobial resistance mechanisms. He holds a B.S. from Illinois State University (1993), a Ph.D. from Purdue University (2000), and completed a postdoc at Washington University in St. Louis (2000-2002).

Research interests include bacteria-host interactions, antibiotic development, immunomodulation, and advanced spectroscopic techniques. His lab employs biophysical and analytical chemistry methods, collaborating with molecular biology and immunology experts to combat wound infections and sepsis.

Key innovations include PEG350-BPEI, a compound neutralizing bacterial virulence factors across Gram-negative and Gram-positive pathogens while reducing inflammation. This work aligns with the 2020-2025 U.S. National Action Plan against antibiotic-resistant bacteria.

No scientific awards are explicitly listed in the provided text. His research has implications for wound care, infection prevention, and improving antibiotic efficacy through multi-targeted approaches.