Charles Brenner

Charles Brenner is the Alfred E. Mann Family Foundation Chair in Diabetes and Cancer Metabolism and Professor at the Department of Diabetes & Cancer Metabolism, Beckman Research Institute, City of Hope, Duarte, CA. He previously held leadership roles at the University of Iowa, Dartmouth Medical School, and Thomas Jefferson University.

His research focuses on disturbances in nicotinamide adenine dinucleotide (NAD) in metabolic stress-related diseases, including diabetes, cancer, postpartum, coronavirus infection, and neurodegenerative conditions. He pioneered the discovery of nicotinamide riboside as a vitamin precursor of NAD and developed quantitative metabolomic technologies to study NAD system dysregulation.

Education:

• Ph.D. in Cancer Biology, Stanford University (1988-1993)
• B.A. with honors in Biology, Wesleyan University (1979-1983)

Key Research Areas: NAD Metabolomics, Systems Biology, Coronavirus Biology, Postpartum & Lactation, Diabesity, Cancer Targeting. His work spans translational applications of NAD precursors to address metabolic dysfunction in diverse pathological contexts.

Scientific Awards:

• Fellow of the American Association for Advancement of Science (2012)
• ASBMB Award for Exemplary Contributions to Education (2016)
• Dartmouth Technology Transfer Innovation Award (2018)
• American Society of Nutrition Mary Swartz Rose Award (2020)

Professional Leadership: He has chaired editorial boards (ASBMB Today), served on publications committees (ASBMB), and co-chaired FASEB conferences on NAD metabolism. His lab at City of Hope continues to explore NAD-based interventions for diseases like fatty liver, diabetes, and cancer.