Charles Bieberich

Charles Bieberich is a Professor in the Department of Biological Sciences at the University of Maryland, Baltimore County (UMBC), where he conducts research at the intersection of developmental biology and cancer. He maintains an active laboratory and teaches courses in developmental biology and cancer biology.

Education:

• Postdoctoral Training, Yale University, 1990
• PhD, Johns Hopkins University, 1987

His research focuses on the molecular mechanisms linking development and disease, particularly in prostate cancer. He investigates the regulation and function of the NKX3.1 tumor suppressor gene and other prostate-restricted transcription factors. His work spans from whole-animal models to biochemical analysis of protein modifications, employing genetic, cellular, and molecular approaches to understand cancer initiation and progression.

The trend in his recent publications reflects a sustained focus on prostate cancer biology, particularly the regulation of NKX3.1 through post-translational modifications, the role of MYC and PTEN in metastasis, and the use of transgenic models for conditional gene expression. His work integrates developmental pathways with oncogenic signaling, highlighting key regulatory nodes with therapeutic potential.

No specific scientific awards are listed in the provided text.

Bieberich advises graduate students and leads a research group that includes an Assistant Research Scientist and several graduate trainees. His lab investigates molecular pathways in prostate development and carcinogenesis. He has not reported any external grants in the provided text, but his extensive publication record suggests sustained research funding.

His laboratory is located in the Biological Sciences Building (rooms 204/217/220/222) at UMBC, where his team conducts research on gene regulation, signal transduction, and cancer models using mouse systems and molecular techniques.