معرفی
Chandra Mohan is the Cullen Distinguished Professor of Biomedical Engineering at the University of Houston’s Cullen College of Engineering. With a background in Pathology, Rheumatology, and Immunology, his research focuses on autoimmune diseases like lupus nephritis, leveraging proteomics, bioengineering, and machine learning to discover biomarkers and diagnostic tools. He leads the Mohan Lab, which has secured over 20 years of NIH funding, developing innovative approaches such as smartphone-based urine testing and AI-driven histopathology analysis. His work bridges basic science and clinical translation, addressing end-organ damage in lupus and cancers.
Education: Medical training at Singapore General Hospital, doctoral work at Tufts University, and postdoctoral research on murine lupus genetics. Formerly held the MGee Chair in Arthritis Research at UT Southwestern Medical Center.
Research interests include:
- Biomarker discovery for lupus nephritis and inflammatory bowel disease
- Non-invasive diagnostics using urine, saliva, and stool proteomics
- Application of OMICs technologies to autoimmunity and cancer
- Optical imaging techniques for monitoring fibrosis in systemic sclerosis
Key achievements include over 250 peer-reviewed publications, 12 patents, and leadership roles in the American Society of Clinical Investigation and Henry Kunkel Society. Current projects involve 10,000-plex proteomic screens for colorectal cancer and IBD biomarkers, AI-driven nephropathology classification, and bioartificial spleen devices for immunotherapy.
Labs/Teams: Mohan Lab (20+ members), Houston Omics Collaborative, and interdisciplinary partnerships with clinicians and engineers.
