Celia Shiau

Celia Shiau, PhD, is an Associate Professor at the University of North Carolina at Chapel Hill, affiliated with the UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center. Her research focuses on macrophage biology with specific emphasis on their roles in nervous system development and tissue homeostasis.

• Research Pillars: Macrophage ontogeny, microglia function in healthy brains, and cross-species immune mechanisms
• Technologies: Multi-omics integration, CRISPR screens, live imaging, and functional genomics

Analysis of her 15 most recent publications reveals consistent exploration of macrophage differentiation, neuroimmune interactions, and evolutionarily conserved regulatory mechanisms. The work spans zebrafish developmental models to human disease implications, with particular attention to Irf8 signaling, phosphatidylserine receptors, and intestinal macrophage-microbiota dynamics.

Key grants include multiple NIH awards (F32 NS067754, R01 NS065787, R56 HL125040) supporting her investigations into macrophage programming and public health implications for inflammation-related disorders.