معرفی
Cathryn R. Nagler is the Bunning Family Professor in the Biological Sciences Division at the University of Chicago, affiliated with the Pritzker School of Molecular Engineering and the College. She holds leadership roles in immunology organizations such as the American Association of Immunologists (AAI), where she serves as Program Chair and Distinguished Fellow. Her research focuses on the microbiome's role in food allergy, oral tolerance, and epithelial barrier function. Nagler graduated from Barnard College, earned her PhD from NYU Grossman School of Medicine, and completed postdoctoral training at MIT. She has pioneered synbiotic therapies for food allergies through her start-up ClostraBio. Awards include the 2017 Distinguished Faculty Award and inclusion in Crain’s Chicago Business Tech Top 50 Women (2018).
Her work integrates microbiology, immunology, and biomedical engineering to develop treatments for immune-mediated diseases. Key contributions include identifying microbial metabolites like butyrate and Clostridia species as protective factors against food allergies. She explores mechanisms linking gut microbiota to vaccine efficacy and intestinal barrier integrity. Current projects involve prodrug copolymers for targeted SCFA delivery and investigating how diet and microbiome interactions influence allergy susceptibility.
Nagler’s lab bridges basic research and translational medicine, with over 100 peer-reviewed publications. Her honors include the AAAAI Foundation Lectureship and Siegel Lectureship. She advocates for program innovation in academic medicine and serves on review panels for immunology and clinical research. Future directions aim to advance microbiome-based therapies and understand the global health impacts of microbiome dysbiosis.
