Casey Dorr

Dr. Casey Dorr is an Associate Professor in the Department of Medicine, Division of Nephrology and Hypertension at the University of Minnesota. Their primary research investigates pharmacogenomics, kidney transplantation outcomes, and interactions between immunosuppressive drugs and the gut microbiome. They specialize in genetic determinants of drug metabolism (e.g., tacrolimus, mycophenolate) and microbial influences on pharmacotherapy.

Research interests span:

• Pharmacogenomics: Genetic variants affecting immunosuppressant dosing and toxicity.
• Microbiome Interactions: Gut microbiota's role in drug enterohepatic recirculation.
• Transplantation Science: Biomarkers for graft survival and rejection in diverse populations.
• Genomic Technologies: CRISPR models, spatial transcriptomics, and polygenic risk scores.

Recent publications (2023–2025) demonstrate a focus on precision medicine in nephrology, with recurring themes of microbial metabolism of immunosuppressants, genetic predictors of drug response, and health disparities in transplant outcomes. Studies utilize longitudinal cohorts, next-generation sequencing, and digital spatial profiling to advance personalized therapeutic strategies.