Mark Liberman is a Trustee Professor at the University of Pennsylvania , holding appointments in the Department of Linguistics and Department of Computer and Information Science . He serves as Director of the Linguistic Data Consortium and Faculty Director of Ware College House . His career spans linguistics, speech technology, and computational methods. Education: Harvard University (1965-1969), MIT (M.S. 1972, Ph.D. 1975) Professional Experience: AT&T Bell Laboratories (1975-1990), University of Pennsylvania (1990-present) His research interests include: Corpus-based Phonetics : Analyzing speech patterns via large-scale datasets. Clinical Applications : Developing speech biomarkers for neurodegenerative diseases. Tonal Phonology : Studying lexical tone and intonation in languages like Yoruba and Mandarin. Formal Annotation Models : Creating frameworks for linguistic data standardization. Recent publications highlight automated speech analysis, cross-linguistic prosody, and digital biomarkers for conditions like ALS-FTD and Alzheimer’s. His collaborations span computational linguistics , neurology , and cognitive science . Scientific awards include the IEEE James L. Flanagan Award (2017), Antonio Zampolli Prize (2010), and fellowships from the AAAS and Linguistic Society of America . He advises PhD students May Chan and Jonathan Him Nok Lee and contributes to editorial boards for journals like Cognition and Annual Review of Linguistics . His work bridges speech science , language technology , and neurocognitive research .
Didier Trono is a Full Professor at École Polytechnique Fédérale de Lausanne (EPFL), where he leads the Laboratory of Virology and Genetics (LVG) within the School of Life Sciences. Formerly, from 2004 to 2012, he served as the founding dean of EPFL's Faculty of Life Sciences, orchestrating its development and growth during this formative period. Trono received his medical education at the University of Geneva, followed by clinical training in pathology, internal medicine, and infectious diseases in Geneva and at Massachusetts General Hospital in Boston. His scientific career began at the Whitehead Institute of MIT, and in 1990 he was recruited by the Salk Institute of San Diego to launch an AIDS research center. After seven years in the United States, he returned to Europe and eventually joined EPFL. Dr. Trono's research has evolved significantly over his career. Initially focusing on virus-host interactions, he studied pathogens like HIV and Hepatitis B virus, creating HIV-derived genetic transfer tools that are now successfully used in gene therapy. For approximately the last fifteen years, his research has centered on epigenetics, particularly exploring the impact of retroelements and their control mechanisms on development and physiology of higher organisms, including humans. His laboratory investigates how transposable elements and KRAB zinc finger proteins regulate gene expression, with important implications for understanding cancer biology and developing new diagnostic and therapeutic approaches. Analysis of his recent publications (2022-2024) reveals a strong focus on transposable elements, KRAB zinc finger proteins, and their roles in gene regulation and cancer. His work combines molecular biology, genomics, and bioinformatics approaches to understand how these ancient viral remnants have been co-opted by the host genome to regulate development and cellular functions. The research spans basic molecular mechanisms to potential clinical applications in cancer diagnosis and therapy, with some recent work also addressing SARS-CoV-2 and immune responses. Throughout his career, Professor Trono has mentored numerous PhD students, including Bojkowska Karolina, Brandão Sanches Vong Martins Filipe Amândio, Bulliard Yannick, Coluccio Andrea, Corsinotti Andrea, Coudray Alexandre, De Tribolet-Hardy Jonas Caspar, and Dorschel Iris Arianna. His laboratory has received significant funding to support research at the intersection of virology, genetics, and epigenetics, contributing to EPFL's reputation as a leading institution in life sciences research. The Trono Laboratory continues to be at the forefront of research on retroelements and their regulatory mechanisms, maintaining a vibrant research environment that bridges fundamental biological questions with potential medical applications, particularly in cancer research and precision medicine.
Harris H. Wang is an Associate Professor in the Department of Systems Biology and Department of Pathology and Cell Biology at Columbia University's Vagelos College of Physicians and Surgeons, where he also serves as Interim Chair of Systems Biology. He is affiliated with the Center for Computational Biology and Bioinformatics (C2B2) and the Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS). B.S., Physics and Mathematics, MIT Ph.D., Biophysics, Harvard University Dr. Wang's research lies at the intersection of systems and synthetic biology, focusing on developing foundational technologies for genome engineering, microbiome manipulation, and synthetic genomics. His lab pioneers methods such as MAGE, MAGIC, CAST, and CAMII to enable high-throughput genetic manipulation, in situ microbiome engineering, and AI-driven microbial culturomics. Key research themes include understanding microbial community dynamics, engineering cellular memory systems, designing biocontained genetic circuits, and applying synthetic biology to human health challenges in personalized medicine and infectious disease. His recent publications reveal a strong trend in spatial and functional metagenomics, CRISPR-based microbiome editing, and synthetic biology tools for data storage and genetic stability. The articles span high-impact journals like Nature , Science , and Nature Biotechnology , reflecting his leadership in developing scalable, programmable biological systems. Scientific Awards: NIH Director’s Early Independence Award Forbes 30 Under 30 in Science Sloan Research Fellowship NSF CAREER Award ONR Young Investigator Award Burroughs Wellcome Fund PATH Award Schaefer Scholar Blavatnik National Award Vilcek Prize PECASE Dr. Wang has advised numerous PhD and postdoctoral researchers, many of whom have gone on to independent scientific careers. His lab is supported by major grants from NIH, NSF, DARPA, DOE, and foundations including the Bill & Melinda Gates Foundation and CZ Biohub NY. He is actively involved in educational initiatives, including organizing Columbia’s iGEM team and the Cold Spring Harbor Laboratory Synthetic Biology course. The Wang Lab is based at the Columbia University Irving Medical Center and is part of national consortia such as the Engineering Biology Research Consortium (EBRC) and the Genome Project-Write (GP-Write) initiative. The lab develops and applies cutting-edge technologies in automation, machine learning, and synthetic biology to engineer microbiomes for applications in medicine, global health, and climate change.
Jun Hyung Lee is a Visiting Assistant Professor in the Department of Environmental Biology at SUNY College of Environmental Science and Forestry (ESF). His research focuses on advancing forest tree improvement and conservation through molecular and synthetic biology approaches, with a particular emphasis on enhancing plant resilience to environmental stresses via beneficial microbial interactions. He teaches courses in plant biotechnology and tissue culture methods. Education includes a Ph.D. in Forest Genetics from Purdue University (USA), and M.S. and B.S. degrees in Plant Science from Seoul National University (South Korea). His work integrates cutting-edge genetic engineering techniques with ecological studies to address challenges in plant stress tolerance, symbiosis, and epigenetic regulation. Recent projects include identifying novel symbiosis pathways for thermotolerance and analyzing flooding tolerance in hybrid poplars. Publications highlight contributions to plant-microbe interaction research, synthetic biology applications, and genome editing epigenetic impacts. Collaborations span institutions like Oak Ridge National Laboratory and the University of Georgia, reflecting his transdisciplinary approach to plant science. Lee’s teaching emphasizes practical skills in biotechnology, bridging laboratory innovation with field applications.
Daniel Finley is a Professor of Cell Biology at Harvard Medical School (HMS), leading the Finley Lab focused on the ubiquitin-proteasome pathway and related regulatory mechanisms. He holds academic appointments within the Department of Cell Biology and sits on the Scientific Advisory Boards of Proteostasis and X-Chem Pharmaceuticals. His research investigates proteasome function, ubiquitin-like proteins, and proteostasis roles in diseases like Alzheimer’s and ALS. Dr. Finley earned his undergraduate degree in biochemistry from Harvard University and a Ph.D. in molecular biology from MIT. After postdoctoral training at MIT, he joined HMS in 1988. His lab explores topics including erythroid proteome remodeling, mitochondrial dysfunction, and neurodegenerative disease mechanisms. Key research areas include: (1) Ubiquitin-proteasome pathway regulation, (2) Proteasome structure/function, (3) Nonproteolytic roles of ubiquitination, and (4) Pathophysiological roles of proteostasis defects in diseases. His work bridges basic cell biology with translational medicine, particularly in neurodegeneration and anemia. Finley has secured NIH funding for projects like 'Regulation of Proteasome Activity' (R35GM145246) and 'Erythrocyte maturation through global proteome remodeling' (R01HL153970). Collaborations with industry and academic partners extend his impact in drug discovery and proteasome-targeted therapies. His lab’s contributions include defining ubiquitin chain editing mechanisms, identifying USP14’s role in mitophagy, and elucidating proteostasis defects in Alzheimer's models. Research tools developed include advanced cryo-EM analyses of proteasomal structures and functional assays for ubiquitin system enzymes.
Alexis Battle is an Associate Professor at Johns Hopkins University with appointments in Biomedical Engineering , Computer Science , and Genetic Medicine (secondary). She directs the Malone Center for Engineering in Healthcare and serves as Deputy Director of the Data Science and AI Institute . Educated at Stanford University (PhD in Computer Science, 2013), Battle transitioned to academia after leadership roles at Google. Research Focus: Battle’s work bridges genomics and machine learning , emphasizing the impact of genetic variation on human health. Her lab develops tools like Watershed to predict functional effects of rare variants, aiming to enhance rare disease diagnosis. Key themes include non-coding DNA analysis , personalized genomics , and systems biology , with applications in cardiovascular disease and neurodegenerative disorders . Publications & Awards: Over 60 peer-reviewed articles in journals like Nature , Science , and Genome Biology , with recent emphasis on single-cell transcriptomics , multiomics integration , and telomere biology . Recipient of the President’s Frontier Award (2022), Microsoft Investigator Fellowship (2019), and Searle Scholar (2016). Scientific Awards: 2022 President’s Frontier Award 2019 Microsoft Investigator Fellowship 2019 Johns Hopkins Discovery Award 2017 Johns Hopkins Catalyst Award 2016 Searle Scholar Advising & Funding: Mentors 11 PhD students, 3 undergraduates, and postdoctoral fellows. Her research is funded by NIH, Searle Scholars, and institutional grants. The Battle Lab collaborates on projects like the GTEx Consortium , focusing on gene regulation and clinical genomics .
Florian Huber is a Research Associate at Paracelsus Medical University's Institute of Pharmacology and Toxicology, investigating molecular mechanisms of genetic hearing disorders. His work focuses on ubiquitin-proteasome regulation of pendrin (SLC26A4) variants associated with Pendred syndrome. Recent studies demonstrate how proteasome inhibitors rescue function of pathogenic pendrin mutants, offering therapeutic pathways for hearing restoration. Huber develops experimental and computational approaches to map degradation pathways of membrane transport proteins. He supervises medical doctoral candidates and teaches pharmacology in graduate programs.
Gareth Roberts is an Associate Professor in the Department of Linguistics at the University of Pennsylvania, where he serves as Graduate Chair. He is also a faculty member of the Psychology Graduate Group, founder and director of the Cultural Evolution of Language Lab, and co-director of the Social and Cultural Evolution Working Group at Penn. Roberts earned his PhD in Linguistics from the University of Edinburgh in 2010, following an MSc in Evolution of Language and Cognition (2006) and a BA in German and Russian (2003) from the University of Nottingham. His academic journey includes postdoctoral positions at Yeshiva University and the University of Stirling before joining Penn as an Assistant Professor in 2014, where he was promoted to Associate Professor in 2022. His research focuses on the role of social and communicative pressures in shaping language emergence and evolution. Roberts investigates fundamental questions about linguistic variant spread, phonological system structuring, and how communication shapes linguistic structure. His work bridges linguistics, cognitive science, and cultural evolution through innovative experimental approaches using artificial languages and laboratory simulations. Analysis of Roberts' recent publications reveals a consistent focus on experimental semiotics, with particular attention to social biases in language evolution, phonological organization, indexicality emergence, and the dynamics of linguistic variation. His work often combines computational modeling with human experiments to isolate specific mechanisms driving language change. Linguistic Society of America Cognitive Science Society Philological Society Cultural Evolution Society Roberts has successfully secured substantial research funding including an NSF PAC Grant ($102,648), Penn URF Research Grants ($12,155), MindCORE initiative grant ($600,000), and multiple smaller grants totaling over $20,000. His lab currently includes researchers investigating diverse topics from case and gender marking emergence to AI agent effects on group dynamics, linguistic and genetic data in British history, and phonological space organization. The Cultural Evolution of Language Lab, which Roberts founded and directs, conducts cutting-edge research using experimental semiotics methodologies. Current projects examine how social factors influence language change, the emergence of linguistic structure through communication, and the interaction between iconicity and combinatoriality in communication systems.
Angela D. Kent is a Professor in the Department of Natural Resources and Environmental Sciences at the University of Illinois Urbana-Champaign, where she also serves as Director of the Program in Ecology, Evolution, and Conservation Biology within the School of Integrative Biology. She is affiliated with the Carl R. Woese Institute for Genomic Biology. Her research focuses on microbial communities in agroecosystems and natural environments, particularly their roles in nitrogen cycling, soil health, and sustainable bioenergy production. Key research interests include microbial interactions in plant-microbe systems, the impact of genetic variation in crops on microbial processes, and the ecological and biogeochemical implications of soil microbiomes. She has authored over 99 publications and supervised datasets on topics such as denitrification dynamics, rhizosphere microbiome assembly, and microbial contributions to nitrogen retention. Dr. Kent has received the NACTA Educator Award (2012) and has contributed to high-impact studies on topics like microbial community responses to environmental stressors and the application of stable isotopes in bioenergy research. Her work bridges microbial ecology, agronomy, and environmental science, emphasizing practical solutions for sustainable agriculture and ecosystem management.
Marc V Fuccillo is an Associate Professor of Neuroscience at the Perelman School of Medicine, University of Pennsylvania, where he leads a research laboratory focused on understanding the neural circuit mechanisms underlying behavioral control. His work bridges molecular, synaptic, and behavioral approaches to investigate how striatal circuits regulate mouse behavior from simple motor patterns to complex goal-directed actions. Fuccillo holds dual appointments in the Neuroscience and Cell and Molecular Biology Graduate Groups at Penn and maintains an active laboratory investigating the synaptic and circuit basis of neuropsychiatric disorders. Education: B.A. in Molecular and Cellular Biology and Music Performance (Violin) from Brown University (1998) Ph.D. in Developmental Genetics from New York University School of Medicine (2007) M.D. from New York University School of Medicine (2008) Fuccillo's research centers on the synaptic and circuit mechanisms of behavioral control, with particular emphasis on striatal circuits. His laboratory employs a range of technologies including mouse genetics, in vitro electrophysiology, in vivo imaging, and quantitative behavioral analysis to explore how neural circuits of the striatum regulate behavior and how disruptions in these circuits contribute to neuropsychiatric disorders. His work has particularly focused on autism-associated abnormalities in behavioral control, examining how synaptic adhesion molecules like neuroligins and neurexins shape circuit function and behavior, with significant findings regarding D1 dopamine receptor positive medium spiny neurons in the nucleus accumbens. Analysis of Fuccillo's recent publications reveals a strong focus on striatal circuit function across multiple dimensions. His work spans molecular neuroscience (examining synaptic adhesion molecules), cellular physiology (studying specific neuron types in striatal circuits), systems neuroscience (mapping circuit connectivity), and behavioral neuroscience (quantifying motor learning and decision-making). A unifying theme is how disruptions in specific molecular pathways lead to circuit-level abnormalities that manifest as behavioral phenotypes relevant to neuropsychiatric disorders, with particular attention to autism, OCD, and schizophrenia models. Scientific Recognition: Publications in high-impact journals including Nature Neuroscience, Current Biology, Cell Reports, and Neuron Research supported by multiple NIH grants including NIMH F32, NIMH K01, and HHMI Gilliam Fellowship awards for lab members Fuccillo actively mentors a diverse group of trainees including postdoctoral fellows, graduate students, and undergraduates. His laboratory has produced numerous successful alumni who have gone on to faculty positions, medical residencies, and graduate programs at prestigious institutions. His mentoring approach emphasizes technical skill development across multiple neuroscience disciplines while fostering independent scientific thinking. Current research in his lab is supported by NIH funding focused on understanding the molecular architecture of striatal circuits and their role in behavioral control, with three major research directions exploring molecular logic of striatal circuits, circuit mechanisms of behavioral control, and striatal dysfunction in neuropsychiatric disease models. The Fuccillo Laboratory operates within the Department of Neuroscience at the University of Pennsylvania, with access to state-of-the-art facilities for molecular, electrophysiological, imaging, and behavioral neuroscience research. The lab maintains active collaborations with other neuroscience research groups at Penn and beyond, creating a rich intellectual environment for studying the neural basis of behavior. Current research directions include investigating whether there is a molecular logic to striatal circuit composition, how striatal circuits shape behavioral control, and what mouse models of autism, schizophrenia, and OCD can reveal about striatal circuit dysfunction in disease pathophysiology.
Kathryn Roeder is the UPMC University Professor of Statistics and Life Sciences at Carnegie Mellon University (CMU), affiliated with the Dietrich College of Humanities and Social Sciences and the Departments of Statistics & Data Science and Computational Biology. Her research focuses on developing statistical methods for genetic and genomic data, particularly in identifying autism risk genes and analyzing single-cell multi-omic data. She earned her Ph.D. in Statistics from Penn State University and has been at CMU since 1994, previously serving as Vice Provost for Faculty (2015–2019). Education: Ph.D. in Statistics, Penn State University (1988) B.S. in Wildlife Resources, University of Idaho (1982) Research Interests: Her work integrates modern statistical techniques (high-dimensional statistics, machine learning, networks) to study complex diseases like autism and schizophrenia. Recent efforts include tools for analyzing single-cell RNA-seq and proteomic data, such as UNICORN, DAWN, and SCEPTRE. Key Awards: COPSS Distinguished Achievement Award (2020) National Academy of Sciences Member (2019) COPSS Presidents’ Award (1997) AAAS Fellow (2020) Advising & Grants: She has advised over 20 Ph.D. students, many contributing to landmark studies in autism genetics. Her grants include NIH funding for projects like the Autism Sequencing Consortium. Current research teams focus on computational biology and statistical genetics. Labs & Collaborations: Her lab develops software tools (e.g., TADA, MIND) and collaborates with the Autism Sequencing Consortium and iPSYCH-BROAD Consortium on large-scale genomic studies.
Tianxi Cai, ScD, holds the John Rock Professorship in Population and Translational Data Sciences at the Harvard T.H. Chan School of Public Health and is a Professor of Biomedical Informatics at Harvard Medical School. She directs the Translational Data Science Center for a Learning Health System (CELEHS). Her work bridges clinical and basic science data to advance personalized medicine and disease understanding. Institution: Harvard University Departments: Biostatistics (T.H. Chan School) and Biomedical Informatics (HMS) Key Roles: Faculty member since 2002, NIH-funded researcher, and leader in EHR data analytics Research focuses on biomarker evaluation, predictive modeling, high-dimensional data analysis, and survival analysis. Collaborates with the I2B2 Center to integrate clinical and genomic data. Active in developing semi-supervised learning methods for noisy EHR data and real-world evidence generation. Funding : Recent grants include NIH projects on rheumatoid arthritis treatment response (R01AR080193, R21AR078339) and semi-supervised EHR denoising (R01LM013614). Co-leads initiatives on chronic disease endpoints using multi-source data (U01FD007929). Labs/Teams : Directs CELEHS and leads the Cai Lab, focusing on translational data science and machine learning applications in healthcare.
David S. Eisenberg is a Professor of Chemistry and Biochemistry and Biological Chemistry at the University of California, Los Angeles, where he also serves as Director of the UCLA-DOE Institute for Genomics and Proteomics and as an HHMI Investigator. His research focuses on protein interactions, particularly the structural basis for conversion of normal proteins to the amyloid state and conversion of prions to the infectious state. Dr. Eisenberg earned his undergraduate degree in biochemical sciences from Harvard College and his D.Phil. degree in theoretical chemistry from Oxford University on a Rhodes Scholarship. His postdoctoral research was on ice and water with Walter Kauzmann at Princeton and in protein crystallography with Richard Dickerson. He joined the UCLA faculty after his postdoctoral studies. Dr. Eisenberg and his research group focus on protein interactions in amyloid and prion diseases. These diseases involve protein aggregation where normal functional proteins convert to abnormal aggregated forms. Systemic amyloid diseases like dialysis-related amyloidosis result from fiber accumulation until organ failure, while neurodegenerative diseases like Alzheimer's, Parkinson's, ALS, and prion conditions appear to be caused by smaller oligomers. In 2005, his team determined the atomic-level structure for the amyloid fiber spine, revealing a 'steric zipper' of two parallel beta sheets packed across a dry interface. Since then, they've determined approximately 90 amyloid spines from 15 disease-related proteins. In 2010, they identified the structure of a toxic amyloid-related oligomer consisting of six anti-parallel beta strands forming a cylindrical barrel. His recent publications demonstrate continued innovation in amyloid research, with focus areas including structural prediction of amyloid formation, mechanisms of tau fibril disassembly in Alzheimer's disease, cryo-EM analysis of amyloid polymorphism, and structure-based design of inhibitors for amyloid toxicity. His work integrates computational, structural, and biochemical approaches to understand protein aggregation across multiple disease contexts. Dr. Eisenberg has received numerous prestigious awards and honors: National Academy of Sciences Member American Philosophical Society Member Institute of Medicine Member Howard Hughes Medical Institute Investigator Biophysical Society Emily M. Gray Award Harvard Westheimer Medal UCLA Seaborg Medal Technion - Israel Institute of Technology Harvey Prize in Human Health As Director of the UCLA-DOE Institute for Genomics and Proteomics and an HHMI Investigator, Dr. Eisenberg leads significant research initiatives in protein structure and aggregation. His laboratory combines X-ray crystallography, bioinformatics, and biochemical techniques to investigate protein interactions, with particular emphasis on amyloid-forming proteins and their role in disease. The Eisenberg Lab, located in Boyer Hall at UCLA, maintains an active research program investigating the structural basis of protein aggregation. The lab continues to build on its landmark discoveries of amyloid structures while exploring new frontiers in understanding protein misfolding diseases and developing potential therapeutic interventions.
David Vocadlo is a Distinguished Professor of Chemistry and Molecular Biology & Biochemistry at Simon Fraser University (SFU), holding the Canada Research Chair in Chemical Biology. His research focuses on Chemical Glycobiology, investigating carbohydrate-processing enzymes and developing chemical tools to study glycan roles in health and disease. His lab explores O-GlcNAc signaling, neurodegenerative disorders (e.g., Alzheimer’s, Parkinson’s), and enzyme inhibitors for therapeutic applications. Education: PhD from University of British Columbia (UBC), followed by a CIHR postdoctoral fellowship at UC Berkeley. Key roles include E.W.R. Steacie Memorial Fellow and Royal Society Fellow. Research highlights include O-GlcNAcase inhibitors for neuroprotection, glycan structure-function relationships, and enzyme activity imaging tools. Collaborates globally with experts in glycobiology and employs cutting-edge techniques like chemical synthesis, mass spectrometry, and live-cell imaging. Awards: Distinguished Professor title, Canada Research Chair, Royal Society Fellowship. Active in training researchers through SFU’s graduate programs, emphasizing interdisciplinary approaches. Lab members work on topics ranging from enzyme mechanisms to disease modeling.
Farnoush Banaei-Kashani is an Associate Professor (Tenured) in the Department of Computer Science and Engineering at the University of Colorado Denver. She also holds an Adjunct Associate Professor position in the Department of Mathematical and Statistical Sciences. As the founder and director of the Big Data Management and Mining Lab (BDLab), she leads multiple GAANN Fellowship Programs, including BDSE (Big Data Science and Engineering), DDC (Data-Driven Cybersecurity), and II (Infrastructure Informatics). She directs the 'Data Science in Biomedicine' MS Track and focuses on data-driven decision systems (DDSs), integrating machine learning and big data analytics into healthcare, energy, transportation, and environmental applications. Education: Details not explicitly provided in the text. Her research spans data management cycles for DDSs, addressing challenges like big data volume, velocity, and variety. Key projects include iWatch (crime surveillance), POCM (mobility monitoring), and GeoSIM (urban texture documentation). She teaches courses such as Machine Learning Systems, Big Data Science, and Data Mining. Publications highlight advancements in sea ice classification, federated learning, proteomic networks, and privacy-preserving AI. Her work is funded by NSF, NIH, DOT, and industry partners like Google and IBM. She has advised numerous students and contributes to academic leadership as editor, conference chair (ACM SIGSPATIAL 2018/2019), and program committee member for venues like SIGMOD and KDD.
