Carsten Berndt

PD Dr. rer. nat. Carsten Berndt leads research at the Department of Neurology, Heinrich Heine University Düsseldorf, focusing on thioredoxin-family oxidoreductases. His work bridges redox biology, iron homeostasis, and neuroinflammatory disease mechanisms.

• Medical Faculty affiliation
• Director of Thiology research group

Research explores:

• Redox-controlled post-translational modifications
• FeS cluster biosynthesis in neurodevelopment
• Neuroinflammation and regeneration processes
• Ferroptosis sensitivity in brain cells
• Tumor cell invasion mechanisms

Recent publications highlight thioredoxin family enzymes' roles in:

• Iron homeostasis (2020, 2011)
• Neuroglia migration (2022)
• GPX4-mediated ferroptosis prevention (2018)
• 2024 work on PRDX6 and selenium utilization