معرفی
Carlos J. Bustamante is a Professor at the University of California, Berkeley, with appointments in the Departments of Molecular and Cell Biology, Chemistry, and Physics. He holds the Raymond and Beverly Sackler Professorship in Biophysics and leads the Bustamante Lab, focusing on structural characterization of nucleo-protein assemblies and single-molecule manipulation techniques.
- Education: B.S. from Universidad Peruana Cayetano Heredia, M.S. from Universidad Nacional Mayor de San Marcos, Ph.D. from UC Berkeley.
His research spans biophysical chemistry, structural biology, and molecular mechanisms of gene expression, utilizing high-resolution scanning force microscopy (SFM) and optical tweezers to study transcription complexes, chromatin structure, and molecular motors. The lab investigates mechanical unfolding of proteins and mechano-chemical conversion processes in macromolecules.
Professor Bustamante has been recognized as a Searle Scholar, Alfred P. Sloan Fellow, Howard Hughes Medical Institute Investigator, and Fellow of the American Physical Society. His work bridges physics, chemistry, and biology through innovative single-molecule techniques.
- Searle Scholar (1984)
- Alfred P. Sloan Fellow (1985)
- Howard Hughes Medical Institute Investigator (1994-1998, 2000)
- Fellow of the American Physical Society (1995)
His laboratory develops cutting-edge methods for studying macromolecular mechanics, including SFM cantilevers, laser tweezers, and magnetic beads. Current projects examine transcription regulation, nucleosome interactions, and energy functions of protein unfolding under varying conditions.
