معرفی
Bruce Tidor is a Professor of Biological Engineering and Computer Science at the Massachusetts Institute of Technology (MIT), leading the Tidor Lab. His research focuses on computational and systems biology, integrating principles from biophysics, artificial intelligence, and applied mathematics to study complex biological systems at molecular and systems levels.
Research Interests:
- Protein and nucleic acid structure-function analysis
- Computational design of proteins and ligands
- Gene expression networks and systems biology modeling
- Drug resistance mechanisms and therapeutic design
Lab Activities: The Tidor Lab develops methods for analyzing biomolecular interactions, parameterizing biological networks, and optimizing drug resistance strategies. Notable projects include studying calcium sensor design, oscillatory biological systems, and mechanotransduction in proteins such as FAT domains.
Collaborations and Grants: Ongoing work includes MIT-Skoltech collaborations, computational re-engineering of enzymes, and modeling cytokine interactions. The lab has advised numerous PhD and master’s students in biological engineering and related fields.
