Bruce Pawel

Bruce R. Pawel, M.D. is a Clinical Professor of Pathology and Laboratory Medicine at the Keck School of Medicine, University of Southern California (USC) and serves as the Chief of Anatomic Pathology at Children’s Hospital Los Angeles (CHLA). His work focuses on the molecular and histopathologic diagnosis of childhood solid tumors, particularly neuroblastoma, rhabdomyosarcoma, and malignant rhabdoid tumors, with expertise in immunohistochemistry, digital pathology, and murine tumor models.

Dr. Pawel is actively involved in team-based translational research, validating therapeutic targets through immunohistochemical analysis and collaborating with physician-scientists in projects such as ALK-driven neuroblastoma therapy and DICER1-associated tumor immunoprofiling. His recent publications highlight advancements in immunotherapeutic targets (e.g., DLK1, GPC2) and genomic profiling of pediatric tumors.

• Scientific Awards:
  • Certificate of Appreciation, American Board of Pathology (2018)
  • 10-year service on Pediatric Pathology Test Development Advisory Committee
• Leadership Roles:
  • Editorial Board, Pediatric and Developmental Pathology and Modern Pathology
  • Resident Tutor, IPPA Advanced Course in Pediatric Pathology
  • COG Responsible Investigator and Mentor, COG Young Investigator Program

Dr. Pawel’s research bridges histopathology, proteomics, and clinical trial support, with a focus on improving outcomes for children with aggressive solid tumors.