Brian W. Pogue

Brian W. Pogue, Ph.D., is the Robert A. Pritzker Chair in Biomedical Engineering at Dartmouth College's Thayer School of Engineering, with a joint appointment as an Honorary Fellow in Medical Physics at the University of Wisconsin-Madison. His academic background includes a Ph.D. in Medical/Nuclear Physics from McMaster University and a Research Fellowship at Harvard Medical School's Wellman Center for Photomedicine. He has led significant administrative roles, including Dean of Graduate Studies at Dartmouth (2008–2012) and Chair of Medical Physics at Wisconsin (2022–2025).

Research Focus: Dr. Pogue pioneers Optics in Medicine, specializing in cancer imaging, photodynamic therapy, and surgical guidance. His work integrates fluorescence imaging, radiation therapy monitoring, and molecular diagnostics to improve cancer treatment precision. Key innovations include Cherenkov imaging for radiotherapy dosimetry and hypoxia-sensitive probes for tumor resection.

Publication Trends: Recent articles (2023–2025) emphasize real-time surgical guidance, hypoxia quantification, and multimodal imaging systems. Dominant themes include fluorescence tomography, radiation dosimetry, and low-cost diagnostic devices, reflecting a translational focus from preclinical validation to clinical applications.

Awards & Honors:

• Fellow, Optica (formerly OSA)
• Fellow, American Institute for Medical and Biological Engineering (AIMBE)
• Fellow, American Association of Physicists in Medicine (AAPM)
• Fellow, SPIE (International Society for Optics and Photonics)

Funding & Innovation: Continuously funded by the NIH since 2001 ($52M+ total), Dr. Pogue founded three startups: DoseOptics LLC (radiotherapy dose imaging) and Hypoxia Surgical LLC (tissue hypoxia cameras), bridging academic research to clinical tools.