Brian Orr

Brian Orr, MD, MS, is an Assistant Professor in the Department of Obstetrics and Gynecology at the Medical University of South Carolina (MUSC), affiliated with Hollings Cancer Center. He specializes in gynecologic oncology, focusing on minimally invasive surgery, chemotherapy, and hyperthermic intraperitoneal chemotherapy (HIPEC) for gynecologic cancers. Dr. Orr’s clinical and research expertise includes translational clinical trial development for ovarian, uterine, cervical, and vulvar cancers, with a particular emphasis on immunotherapy and targeted therapies.

Education:

• Medical School: University of Tennessee Health Science Center College of Medicine (2010)
• Medical School: University of Pittsburgh (2020)
• Residency: University of South Florida College of Medicine (2014)
• Fellowship: Magee Womens Hospital of the UPMC Health System (2017)
• Master’s Degree: University of Pittsburgh (Clinical and Translational Science)

Research Focus: Dr. Orr’s work bridges clinical practice and research, advancing therapies for gynecologic malignancies through innovative clinical trials. His research integrates immunotherapy and targeted drug development to improve patient outcomes. He actively participates in multidisciplinary oncology care and surgical innovation, including robotic and minimally invasive techniques.

Professional Affiliations: Dr. Orr is board-certified in Obstetrics & Gynecology and Gynecologic Oncology. He contributes to MUSC’s academic mission through teaching and mentoring, though no specific advisees are listed. His clinical practice is integrated with Hollings Cancer Center’s comprehensive care model.