Bram de Laere

Bram de Laere is a Research Fellow at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. His research focuses on translational cancer genomics with emphasis on liquid biopsy applications in prostate cancer, contributing to international clinical trials and collaborative projects aimed at advancing precision oncology for advanced prostate cancer patients.

His primary research interests center on Cancer and Oncology and Medical Genetics and Genomics. He specializes in circulating tumor DNA (ctDNA) analysis for biomarker discovery in metastatic castration-resistant prostate cancer (mCRPC), investigating genomic alterations driving treatment resistance and disease heterogeneity through next-generation sequencing and computational approaches.

Analysis of his publication record reveals consistent focus on liquid biopsy development, particularly ctDNA profiling for prognostic modeling and treatment selection. His work demonstrates strong interdisciplinary collaboration across oncology, genomics, and bioinformatics, with significant contributions to understanding androgen receptor signaling, DNA repair defects, and clinical implementation of genomic biomarkers in prostate cancer management.