Bram Agema

Bram Agema is a Researcher at Erasmus MC, specializing in Medical Oncology with a focus on pharmacokinetics and model-informed precision dosing. His work integrates pharmacometrics to optimize drug therapies in oncology and other clinical settings. He holds a doctoral degree from Erasmus University Rotterdam, awarded in June 2025 for his thesis on data-driven dosing strategies in oncology.

Key research areas include drug exposure-response relationships, individualized therapy optimization, and predictive modeling of chemotherapy regimens. Recent projects address challenges in transitioning between subcutaneous and transdermal drug administration, nintedanib pharmacokinetics in pulmonary fibrosis, and ensemble modeling for precision dosing.

His publications emphasize translational research bridging pharmacokinetic theory to clinical practice, with contributions to journals like Drugs, Journal of Pain and Symptom Management, and Clinical Pharmacokinetics. Collaborations span multidisciplinary teams at Erasmus MC and other institutions, focusing on improving treatment efficacy and safety through advanced dosing strategies.