Boris Musset

Boris Musset is a Professor at the Institute of Physiology and Pathophysiology, Paracelsus Medical University (Salzburg, Austria). His primary affiliation is with the Medical Faculty, focusing on biophysical and molecular aspects of voltage-gated proton channels and their roles in cellular processes. He has been active in research since 2002, publishing extensively on topics including proton channel structure-function relationships, cancer-associated mutations, and membrane biology.

Education and Background
While specific educational details are not provided, his academic titles include DDr. (Doctor of Medicine) and Universitätsprofessor (Professor), indicating advanced training in medical and biological sciences.

Research Interests
Dr. Musset’s work centers on voltage-gated proton channels (HV1/HVCN1), exploring their roles in immunity, cancer, and male infertility. Key themes include:

• Molecular mechanisms of proton channel regulation
• Biophysical properties of somatic mutations in cancer
• Interaction with membrane components like stomatin
• Evolutionary diversity of proton channels in organisms like molluscs

His recent studies highlight the implications of channel dysfunction in disease pathways.

Grants and Projects

• Lead Investigator: "The human voltage-gated proton channel as a drug target to treat male infertility" (2017-2018)
• Co-Principal Investigator: "Does blood glucose concentration affect the respiratory burst of human immune cells?" (2018-2019)

Professional Activities

• Organized workshops on cellular biophysics (e.g., DGfB Section III Workshop, 2024)
• Presented at conferences including the German Biophysical Society meeting and CRC 1078 Symposium

Labs/Teams
Leads a research group investigating proton channel biology with collaborations on membrane protein dynamics and cancer-related mutations.