معرفی
Bing Chen is a Professor of Pediatrics and a faculty member at Harvard Medical School, affiliated with Boston Children's Hospital. His research focuses on elucidating the molecular mechanisms of HIV-1 and SARS-CoV-2 viral entry, structural biology of envelope/spike proteins, and antibody neutralization for vaccine design.
- Institution: Harvard University (Boston Children's Hospital)
- Research: Structural analysis of viral envelope proteins, host receptor interactions, and immunogen design.
His work spans HIV-1 and SARS-CoV-2 studies, emphasizing conformational dynamics and antibody evasion. Recent publications highlight structural insights into spike protein mutations and vaccine development strategies.
Current efforts include reconstitution of viral membrane fusion reactions and design of immunogens for broadly neutralizing antibodies. He utilizes X-ray crystallography, NMR, and cryo-electron microscopy to generate molecular 'movies' of viral entry processes.
