معرفی
Betty Leibold is a Professor at the University of Utah in the Department of Internal Medicine. Her research focuses on iron metabolism, diabetes, and mitosis, with a particular emphasis on iron regulatory proteins (IRPs) and their role in cellular homeostasis.
Education:
- B.S., State University of New York
- Ph.D., Massachusetts Institute of Technology
Research Interests include understanding how eukaryotic cells sense and respond to iron, the mechanisms of IRP2 regulation via ubiquitin ligases and phosphorylation, and the link between iron dysregulation and diseases like diabetes and neurodegenerative disorders. Her lab employs Caenorhabditis elegans and transgenic mice models to study these pathways.
Publications highlight her work on IRP2's role in iron-dependent tRNA modification, HIF-1 regulation of iron homeostasis in worms, and the molecular mechanisms of IRP2 degradation. Keywords span iron metabolism, protein regulation, cell signaling, genetic models, and disease pathogenesis.
