Bethany Caulkins

Bethany Caulkins serves as an Assistant Professor in the Chemistry Department at Scripps College, where she leads research at the intersection of physical chemistry and structural biology. Her work leverages advanced nuclear magnetic resonance (NMR) methodologies to investigate fundamental biochemical processes, with particular emphasis on enzyme mechanisms and protein dynamics.

Her primary research domains include NMR Spectroscopy, Enzyme Mechanisms, and Protein Dynamics, with specialized focus on tryptophan synthase catalysis, metabolomics, and neurodegenerative disease models. She employs cutting-edge techniques such as NMR crystallography, dynamic nuclear polarization, and solution-state NMR to characterize enzyme active sites, protein folding intermediates, and molecular recognition events in lipid environments.

Analysis of her publication trajectory (2015-2025) reveals sustained investigation into tryptophan synthase intermediates using multi-technique approaches, with recent expansion into metabolomics and rodent model systems. Her work consistently bridges structural characterization and functional mechanism studies, demonstrating expertise in both solid-state and solution NMR methodologies applied to complex biological systems.