معرفی
Bertrand CARIOU is a Professor in Endocrinology at Nantes University and CHU Nantes, serving as Director of the Thorax Institute. He heads the CIC Endocrinology-Diabetology-Nutrition and leads Team 4 "Cardiometabolic Diseases" at Inserm UMR 1087 / CNRS UMR 6291. Additional roles include Vice Dean of Research at the Medical School and Vice Director of Research at Pôle Santé, Nantes Université. He co-leads the FHU GO-NASH network focused on metabolic liver diseases.
Education
- 2008: HDR (Habilitation to Supervise Research), Nantes University
- 2003: PhD, University Paris XI
- 2003: MD in Endocrinology, Diabetology and Metabolic Diseases, Nantes University
- 2000: MSc, University Paris XI
Research Focus
Dr. CARIOU leads translational research in cardiometabolic diseases with expertise in PCSK9 biology, lipoprotein metabolism, and genetic determinants of cardiovascular risk. His multidisciplinary team integrates clinical research with molecular biology and omics approaches to develop novel therapeutic strategies. Key research domains include atherosclerosis pathophysiology, dyslipidemia mechanisms, and metabolic dysfunction-associated steatohepatitis (MASH).
Research Leadership
Directs a team of 12 permanent researchers (including 5 clinicians), 10 PhD students, and 13 research assistants. Oversees the Clinical Investigation Center conducting phase 2/3 trials and proof-of-concept studies. Leads nationwide programs including RHU CHOPIN for hypercholesterolemia management and MEDITWIN for ASCVD digital twin development.
Awards & Recognition
- Auguste Loubatières Prize (2017)
- Apolilinaire Bouchardat Prize (2009)
- INSERM Interface Contract (2009-2014)
Grant Leadership
- MEDITWIN Project (2024-2029): €1.99M - Digital twins for ASCVD risk prediction
- ANR GENESIS (2022-2024): 410k€ - Gpr146 target validation
- FRM Team Grant (2020-2023): 380k€ - LDL determinants research
- CORONADO PHRC (2020-2022): 378k€ - COVID-diabetes outcomes
- AMGEN PCSK9 Grant (2018): Multi-million € - Consortium management
