معرفی
Bertram Jacobs is a Professor in the School of Life Sciences at Arizona State University (ASU), specializing in virology. He holds affiliations with the Biodesign Center for Mechanisms of Evolution, the ASU-Banner Neurodegenerative Disease Research Center, and the Center for Evolution and Medicine. His research focuses on developing vaccines for HIV and neurodegenerative diseases, particularly leveraging poxviruses like vaccinia to combat infectious agents, cancer, and bioterrorism threats.
Jacobs earned a PhD in Biochemistry from the University of California-Berkeley (1981) and a BS in Biology from Rutgers University (1974). He has led global health initiatives, including annual summer programs in sub-Saharan Africa to teach AIDS prevention. His work emphasizes viral immunology, with a focus on the vaccinia virus's role in immune evasion and vaccine development.
Research interests span viral pathogenesis, vaccine design, and the evolution of viral immune strategies. His studies highlight mechanisms like the vaccinia E3L gene's inhibition of interferon responses, critical for vaccine safety and efficacy. Jacobs has contributed to over 100 publications, advancing understanding of viral-host interactions and translational medicine.
His grants include NIH-supported projects on poxvirus vaccines, HIV vector development, and smallpox countermeasures. Jacobs advises students in virology and molecular biology, mentoring through undergraduate and graduate research programs. He is also actively involved in scientific service, including editorial roles for Journal of Virology and leadership in the University Biosafety Committee.
