Bernhard Palsson

Bernhard Palsson is the Scientific Director at the Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain), Technical University of Denmark (DTU). His research focuses on systems biology, metabolic engineering, and computational modeling in microorganisms such as Escherichia coli and Yarrowia lipolytica.

• Key roles: Scientific Director, Researcher, PhD Supervisor
• SDG contributions: Biosustainability, Antibiotic Discovery, Climate Action

Research Interests:
Palsson's work spans metabolic pathways, regulatory networks, and genome-scale modeling. He explores chemical stress tolerance mechanisms, pangenome structures, and integrates machine learning with transcriptomic data to advance biosynthetic applications. His projects include antibiotic discovery via computational resources and metabolic model reconstruction for Lactobacillus and Escherichia coli species.

Recent Article Trends:
His 2025 submissions highlight interdisciplinary approaches combining machine learning and experimental evolution to enhance biochemical production and address antibiotic resistance. Topics include transcriptional network analysis, pangenome decomposition, and metabologenomic modeling, emphasizing scalability and data-driven methodologies.

Supervision & Collaboration:
Palsson mentors PhD students like Omid Ardalani and collaborates on projects such as iimena (Integration of Informatics and Metabolic Engineering for Novel Antibiotics) and pangenome metabolic model reconstruction. His team includes researchers from DTU and international institutions.

• Projects:
  • iimena: Novel Antibiotic Discovery (2017–2023)
  • Lactobacillus Pangenome Modeling (2021–2025)
• Networks:
  • Collaborated with institutions in 12+ countries
  • Co-authorships in Escherichia coli and Yarrowia lipolytica studies