Bernd Reif

Prof. Dr. Bernd Reif holds the Associate Professorship of Solid-State NMR Spectroscopy at the Department of Bioscience, TUM School of Natural Sciences, Technische Universität München. His research focuses on structural characterization of amyloid fibrils and membrane proteins using MAS solid-state NMR spectroscopy, particularly investigating Alzheimer's disease β-amyloid aggregation, protein dynamics, and small molecule interactions with pathological aggregates.

• Studied physics and biochemistry at University of Bayreuth
• PhD in organic chemistry from University of Frankfurt am Main (1998)
• Previously professor at Charité University Medical Center and FMP Berlin (2004-2010)

Research interests include:

• Structural analysis of amyloid fibrils
• Mechanistic studies of protein aggregation
• Development of solid-state NMR methods
• Dynamics of isotopically labeled proteins
• Interactions between molecular chaperones and amyloid aggregates
• Membrane protein structure determination

Recent publications highlight:

• Atomic resolution structures of human insulin fibrils
• Modulation of Aβ40 fibril polymorphism by αB-crystallin
• Seeding mechanisms in hIAPP fibril formation
• Quantification techniques in MAS solid-state NMR
• Structural insights into immunoglobulin light chain aggregation

Scientific recognition:

• Günther Laukien Prize (2017)
• Emmy Noether Fellowship (2000)
• Richard Wagner Scholarship (1993)

He teaches advanced courses in:

• Biological Solid-State NMR (CH5174)
• Chemie II for Engineering Science B.Sc.
• Methods of Catalysis (CH3242a/b)
• Scientific Workshops (4 SE)