Baoqiang Guo

Dr Baoqiang Guo is a Senior Lecturer in Hematology and Transfusion Sciences at Manchester Metropolitan University. He combines clinical training in hematology with expertise in stem cell and molecular biology research. His work focuses on neurodegenerative diseases, particularly Alzheimer’s, using induced pluripotent stem cell (iPSC)-based models to study microglia/macrophage mechanisms and develop therapeutic strategies.

• Research Interests: Alzheimer’s disease pathogenesis, iPSC-derived macrophage/microglia models, exosome-mediated drug delivery, and anti-inflammatory therapies for neurological disorders.

He investigates CD33 signaling in Alzheimer’s progression and explores high-throughput screening of small molecules to enhance amyloid-β clearance. Additionally, his work utilizes exosomes from iPSC-derived mesenchymal stem cells (iMSCs) to deliver anti-inflammatory drugs across the blood-brain barrier and promote neural regeneration.

Contact: b.guo@mmu.ac.uk | 0161 247 3366 | 220 John Dalton Building (9am–5pm).