معرفی
Professor Aziz Aboobaker holds academic positions at the University of Oxford, including Professor of Comparative and Functional Genomics within the Department of Biology. He is also a Tutorial Fellow at Lady Margaret Hall and serves as Section Head of Evolutionary Biology. His work spans two primary locations: Mansfield Road (OX1 3SZ) and South Parks Road (OX1 3RB), both in Oxford.
His research focuses on regeneration mechanisms and stem cell biology, particularly in planarian flatworms and the amphipod crustacean Parhyale hawaiensis. These models allow exploration of pluripotent stem cells' roles in regeneration, aging, and cancer resistance. Key projects include sequencing Parhyale's genome to study limb regeneration and investigating how conserved molecular pathways regulate stem cell proliferation and differentiation.
Articles across 2024–2018 reveal a sustained emphasis on understanding stem cell dynamics under stress, epigenetic control of regeneration, and the interplay between environmental factors (e.g., calorie restriction) and longevity. His studies also address evolutionary questions, such as conservation of regeneration mechanisms across species and the role of mTOR signaling in stem cell maintenance.
Professor Aboobaker leads the Evolutionary Biology section and collaborates on genomic projects, including transgenesis in Macrostomum lignano and analysis of the tardigrade Hypsibius dujardini. His work bridges fundamental biology with translational insights into aging and regeneration.
