معرفی
Ayman Al Haj Zen is a Visiting Scientist and Research Fellow at the University of Oxford, based in the Division of Cardiovascular Medicine and the Target Discovery Institute (TDI). He holds an MD and PhD from the University of Paris VII (2006), specializing in vascular repair and atherosclerosis. Prior to Oxford, he conducted postdoctoral research at the London Research Institute and the University of Bristol, focusing on vascular development and ischemia-induced angiogenesis.
His research emphasizes therapeutic angiogenesis, targeting chronic vascular diseases like peripheral arterial disease and non-healing wounds. He employs in vitro angiogenesis assays, high-throughput screening, and quantitative imaging to identify novel therapeutic strategies. Notable findings include the discovery of Tazarotene’s role in wound regeneration and Lacidipine’s effects on vascular lumen expansion.
His work also explores paracrine signaling interactions between microvascular networks and diseased microenvironments using 2D/3D co-culture models and murine models of angiogenesis. This approach aims to identify translational targets for chronic vascular therapies.
Awards:
- Intermediate Research Fellowship from the British Heart Foundation (Oxford Centre of Research Excellence, 2013)
Labs/Teams: Collaborates with the Watkins Group (Inherited Heart Muscle Disease) and the Oxygen Sensing Lab (Peter Ratcliffe group). His research integrates molecular signaling, regenerative medicine, and translational drug discovery.
