معرفی
Audrey Desgrange is a Research Fellow specializing in embryology and morphogenesis, currently developing projects on cellular and molecular mechanisms of heart formation at the Morphogenèse du coeur laboratory. Her work bridges developmental biology and cardiovascular research through advanced phenotyping and genetic analysis.
Her research focuses on embryonic morphogenesis, particularly heart looping and left-right asymmetry. Key interests include:
- Cellular mechanisms driving organ shape acquisition
- Genetic determinants of congenital heart defects
- 3D reconstruction of embryonic development
- Mouse models for human developmental disorders
Recent publications reveal a strong emphasis on asymmetric gene expression (e.g., Notch3, Nodal pathways) and genetic modifiers of structural heart defects. Her work integrates computational modeling with molecular genetics to decode morphogenetic processes.
Dr. Desgrange's doctoral work (2015) examined renal tubule formation across international labs in Paris and Oulu, establishing her expertise in cross-species developmental mechanisms. Her current research program investigates crisscross heart formation and kidney agenesis through innovative imaging pipelines.
