Asta Brogaard Christensen

Asta Brogaard Christensen is a Research Fellow at the Department of Haematology within the Faculty of Medicine at Aalborg University Hospital, Aalborg University. Her research focuses on molecular mechanisms in hematological malignancies, particularly Diffuse Large B-Cell Lymphoma (DLBCL), utilizing advanced genomic techniques to investigate therapeutic targets and drug resistance pathways.

Her primary research interests include Hematology, Oncology, Immunology, and Molecular Biology, with specific emphasis on B cell immunology, CRISPR/Cas9 gene editing, DNA damage response mechanisms, and the role of genes like CDCA2 in lymphoma progression. Her work bridges basic molecular research and clinical applications to improve lymphoma treatment strategies.

Recent publications demonstrate consistent focus on CRISPR-based functional genomics in DLBCL, revealing critical pathways for cisplatin response and identifying CDCA2 as a promoter of cell proliferation and bortezomib sensitivity. These studies establish connections between DNA repair mechanisms, kinase signaling, and therapeutic vulnerability in aggressive lymphomas.