معرفی
Professor Antonis Antoniou is a Professor of Cancer Risk Prediction at the University of Cambridge, working within the Department of Public Health and Primary Care in the School of Clinical Medicine. He serves as Director of the Centre For Cancer Genetic Epidemiology and leads the CRUK Cancer Data Driven Detection (CD3) national strategic initiative.
His educational background includes Actuarial Science from the London School of Economics, an MPhil in Mathematical Statistics, and a PhD in Genetic Epidemiology, all from the University of Cambridge. He was awarded a CRUK Senior Cancer Research Fellowship in 2009, appointed Reader in 2013, and became Professor of Cancer Risk Prediction in 2017.
Professor Antoniou's research focuses on improving cancer risk stratification through multifactorial algorithms using epidemiological, genomic, clinical and demographic data. His work includes characterizing cancer risks for genetically susceptible individuals (particularly BRCA1/2, PALB2, RAD51C, and RAD51D mutation carriers), identifying novel cancer risk factors, and developing clinical tools like the BOADICEA risk prediction algorithm implemented in the CanRisk tool.
His research portfolio encompasses major initiatives including the CD3 Initiative, CanRisk Programme, Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA), EMBRACE study, CANGENE-CANVAR, and RREDD-EHR. These projects collectively aim to revolutionize cancer risk understanding and enable early cancer interception through data-driven approaches.
- CRUK Senior Cancer Research Fellowship (2009)
Professor Antoniou has been instrumental in developing risk prediction models that integrate genetic, epidemiological, and clinical factors to enable personalized cancer screening and prevention strategies. His work bridges the gap between complex genomic data and clinical implementation, with particular emphasis on breast and ovarian cancer risk assessment.
He has lectured on the MPhil in Epidemiology and MPhil in Population Health Sciences since 2010, serving as Academic Course Director for the MPhil in Epidemiology (2016-2021) and academic theme lead for epidemiology (2021-2023).
