Antonio SICA

Antonio SICA is a Full Professor in the Department of Pharmaceutical Sciences at the University of Eastern Piedmont 'Amedeo Avogadro'. With an extensive research career spanning over three decades, he has published 189 research outputs including articles, reviews, and conference contributions. His ORCID profile (0000-0002-8342-7442) documents his significant contributions to immunology and cancer research.

Professor SICA's research primarily focuses on myeloid cells in cancer, particularly tumor-associated macrophages and myeloid-derived suppressor cells. His work explores how these cells contribute to tumor progression, immunosuppression, and response to therapy. Key research areas include immunometabolism, epigenetic regulation of myeloid cells, and the intersection of inflammation with cancer development.

Analysis of his recent publications (2021-2024) reveals a strong emphasis on myeloid cell heterogeneity in cancer, immunometabolic pathways, and the role of myeloid cells in age-related diseases. His 2023-2024 work has particularly examined connections between cancer immunology and infectious diseases like COVID-19, demonstrating how immunometabolic interference affects disease outcomes.

• Advancing the knowledge of human neutrophils displaying polymorphonucler myeloid-derived suppressor cell (PMN-MDSC) functions (2023-2025)
• BioTher19: Biological bases of immune response in fragile COVID-19 patients
• Deciphering the molecular and functional heterogeneity of myeloid cells in cancer (2019-2023)
• Deciphering the epigenetic basis of Myeloid-derived immunosuppression in cancer and therapy (2018-2023)

Professor SICA has supervised 5 students throughout his career and maintains active research collaborations across multiple institutions. His work contributes significantly to UN Sustainable Development Goals related to good health and well-being, particularly through advancing cancer immunology and immunotherapy approaches.