معرفی
Anne-Caroline Chany is a Research Officer at CNRS affiliated with the Institute of Molecules and Materials of Le Mans (IMMM) at Le Mans University, specializing in the total synthesis of bioactive natural products. Her career spans postdoctoral research at Oxford, Le Mans University, and University of Haute-Alsace, plus an ATER position at University of Nantes.
Her academic trajectory:
- PhD (2008-2011) & Postdoc (2011-2012): University of Haute-Alsace, synthesizing mycolactone analogues for Buruli ulcer research under Dr. N. Blanchard
- Postdoc (2013-2015): University of Oxford with Prof. J.W. Burton, developing γ-lactone synthesis methodologies via Marie-Curie IEF Fellowship
- Postdoc (2015-2016): IMMM/Le Mans University with Dr. C. Gaulon-Nourry & G. Dujardin on Peloruside A analogues
- ATER (2016-2017): CEISAM/University of Nantes with Dr. S. Collet on topopyrone synthesis
Chany's research centers on constructing complex natural architectures like mycolactones, Peloruside A, and topopyrones through stereoselective organic synthesis. Her work bridges medicinal chemistry and synthetic methodology, targeting bioactive compounds with therapeutic potential. She employs advanced techniques in γ-lactone formation and molecular analog construction to address challenges in natural product synthesis.
Her scientific output comprises 16 peer-reviewed articles, 1 book chapter, and 1 patent, demonstrating consistent contributions to organic chemistry literature.
Awards:
- Marie-Curie International European Fellowship (2013-2015)
Funded primarily through competitive fellowships including the Marie-Curie grant, Chany collaborates within IMMM's multidisciplinary ecosystem. She leverages the institute's 15+ specialized platforms including organic synthesis labs, X-ray diffraction, NMR, femtosecond laser systems, and electron microscopy facilities to advance her synthetic projects.
