معرفی
Anjum Ansari, PhD, is a Professor in the Department of Physics at the University of Illinois at Chicago (UIC). Her research focuses on biomolecular dynamics, particularly the conformational fluctuations of nucleic acids and protein-DNA interactions. She pioneered laser temperature-jump (T-jump) spectroscopy and fluorescence lifetime measurements to study these processes.
- Education: BS (Physics, 1981) from Indian Institute of Technology; MS and PhD (Physics, 1988) from University of Illinois at Urbana-Champaign.
Her research interests include nucleic acid folding mechanisms, protein-DNA interactions, and DNA damage recognition. Key contributions include studies on hairpin/pseudoknot formation, DNA bending by architectural proteins, and mechanistic insights into nucleotide excision repair via the Rad4/XPC complex.
Her group’s work on supercoiled DNA dynamics and ion-modulated RNA folding pathways bridges experimental and computational biophysics. Collaborations with molecular biologists and computational scientists enhance their interdisciplinary approach.
Recent studies examine DNA deformability in repair processes and mismatch recognition mechanisms using advanced spectroscopic techniques. Her lab (Ansari Lab) actively explores biomolecular dynamics in biologically relevant contexts like looped DNA structures.
