Angela van Tilborg

Angela van Tilborg is a Researcher at Erasmus MC, Erasmus University Rotterdam, specializing in molecular oncology with a focus on genomic and epigenetic mechanisms in bladder cancer, glioma, and meningioma. Her work integrates high-throughput genomic analysis with advanced cell culture models to identify diagnostic biomarkers and therapeutic targets.

Her core research interests include:

• Cancer Genomics: Genome-wide profiling of mutations and structural variants in urological and brain tumors
• Epigenetic Regulation: CpG island methylation patterns as prognostic indicators in early-stage bladder cancer
• Tumor Modeling: Development of primary cell cultures and 3D spheroid systems preserving in vivo genomic signatures
• Molecular Diagnostics: Microsatellite and mutation-based markers for non-invasive cancer detection

Analysis of her 2006-2012 publications reveals consistent innovation in translating genomic findings to clinical applications, particularly in bladder cancer stratification and glioma model validation. Her work demonstrates how epigenetic alterations drive tumor progression while maintaining genomic stability in spheroid cultures, with implications for personalized therapy development.