معرفی
Dr Angela Mousley is a Professor in the School of Biological Sciences at Queen's University Belfast, holding a dual appointment with the Institute for Global Food Security. Her research addresses critical threats to livestock production and global food security posed by nematode pathogens, focusing on novel control target identification within neuropeptidergic systems and functional genomics platform development for validation. With 64 research outputs spanning two decades, she actively supervises postgraduate students and maintains a prominent role in the university's academic structure as evidenced by her office in Room 01.081 and ongoing project involvement.
Her research interests include:
- Nematode pathogen biology and therapeutic resistance mechanisms
- Neuropeptidergic system target prioritization
- Functional genomics for parasitic target validation
- RNA interference applications in helminth studies
- Liver fluke (Fasciola hepatica) molecular characterization
- Antimicrobial peptide discovery in parasite secretions
Recent publications (2024-2025) demonstrate consistent focus on leveraging omics resources across nematode species, bridging model organisms like Caenorhabditis elegans with parasitic nematodes, and extending research to liver fluke stem cell biology. These works reveal strategic trends toward genomic analysis for drug target identification and validation, with direct applications in agricultural and clinical settings to combat antimicrobial resistance.
Scientific recognition includes:
- QUB Team Teaching Award (2018) for curriculum innovation
- Nomination for Staff Excellence Award (2020/21)
Dr Mousley has supervised nine PhD students with projects covering RNA interference susceptibility, drug target validation, antimicrobial activity characterization, and endocannabinoid signaling in parasitic nematodes. She serves as Co-Investigator on the major R1127BSC project (active since July 2023) establishing mass spectrometry proteomic capabilities at Queen's University Belfast, funded through internal research infrastructure grants.
Based in the School of Biological Sciences, she collaborates internationally through the Institute for Global Food Security on projects targeting antimicrobial resistance reduction in agri-food sectors. Her team participates in molecular diagnostic workshops for helminth infections and develops resistance-breaking control strategies, with recent activities including external PhD examinations and integration of bioentrepreneurship into curriculum development.
